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Programmable human vasculature for preclinical drug testing

Perfusure develops perfusable human vascular models that enable researchers to control, measure and reproduce the vascular microenvironment in advanced disease models and drug testing

Mission

Bioengineered Life Solutions

Engineer programmable human vasculature that makes disease modelling and drug testing more predictive, reproducible, and human-relevant.

Team

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Prasanna Padmanaban MSc. Hons, PhD

Founder and Chief Executive Officer

Bioengineer

Prasanna is a vascular bioengineer with expertise in microfluidics, 3D tissue engineering, mechanobiology, and computational vascular modelling. He brings lab-to-product insights, translating advances in vascular biology and bioengineering into technologies with clinical and pharmaceutical relevance. His research experience spans Max Planck Institutes, the University of Twente, EMBL, and Aarhus University.

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Sergio Miguel Castañeda Zegarra, PhD, MBA 

Business Development Consultant

Life Science Strategy & Venture Development

Sergio is a life science strategist with experience spanning translational science, venture capital and business development. He brings bench-to-market insights, bridging scientific innovation with commercial strategy, funding and growth opportunities. At Perfusure, he supports business development, funding strategy and strategic partnerships, helping position the technology for successful translation and commercialisation.

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Praleene Sivapalan MD, PhD

Founder and Chief Medical Officer

Clinician

Praleene is a physician-scientist with experience in anaesthesia, intensive care, and translational medicine. She brings bedside-to-product insights, translating unmet clinical needs and patient perspectives into relevant experimental models and technology development. She helps ensure that Perfusure's innovations remain grounded in real-world clinical challenges.

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Torben Stamm Mikkelsen, PhD

Scientific and Clinical Advisor

Pediatric Oncologist & Associate Professor 

Torben is a clinician-scientist in paediatric oncology. He brings deep expertise in childhood cancers, translational research, and clinically relevant disease modelling. He provides scientific and clinical insights to help ensure that our vascular tissue models address meaningful questions in oncology and support the translation of emerging technologies toward more predictive drug testing and precision medicine.

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Advantages of Our Solutions

Flow-driven Technology for Healthcare

Discover the unique benefits of our cutting-edge solutions tailored to enhance oncology diagnostics, disease modelling, and improve clinical guidance.

Patternable

Engineer defined vascular architectures for tissue- and disease-specific models.

Perfusable

Deliver cells, nutrients and therapeutics through functional human vascular networks.

Programmable

Control flow and vascular conditions dynamically across an experiment.

Platform Technology

One platform | programmable vascular experimentation

Explore our comprehensive range of services designed to ease laboratory experiments and imaging operations. From AI-integrated design to advanced perfusion testing, we are dedicated to driving success in healthcare.

Microfluidic Cartridges

Perfusable human vascular models for reproducible disease modelling and drug-response studies within standardised experimental formats.
 

Programmable Perfusion Solutions

Precise, programmable control of fluid flow and vascular conditions across experiments.

Biological Assays

Disease-specific assays for tumour–vascular interactions, drug response, vascular permeability and toxicity

Automation and Analytics

Real-time experiment control, monitoring and data analysis.

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